Dr. Temperance Brennan (Emily Deschanel) is a gifted anthropologist at the Jeffersonian Institution who writes novels in her spare time. Brennan works very frequently with FBI agent Seeley Booth (David Boreanaz) to help identify cadavers when standard methods are useless. Being a bit at odds with the modern world (a complete lack of familiarity with pop culture or a misunderstanding of movie quotes and slang), she often repeats that she understands the dead better than the living. Her friends from the Jeffersonian are assisting in the investigations: Angela Montenegro (Michaela Conlin), a visual artist creating three-dimensional holograms of crime scenes and hypothetical course of it; Zac Addy (Eric Millegan), Brennan's assistant whose high IQ prevents him from completing several PhDs. The "Happy Bunch" is closed by Dr. Jack Hodgins (T.J. Thyne), who specializes in insects and minerals, and a great supporter of conspiracy theories.