"Fantastic Beasts and Where to Find Them" starts in 1926. Newt Scamander returns from a great expedition to find and describe a number of fantastic animals. His short stay in New York might have gone unnoticed, were it not for a non-spell (i.e. an American Muggle) named Jacob, a misdirected magic coincidence and the escape of some of Newt's fantastic animals. All of this can cause serious trouble for both the magical and non-witchcraft worlds.