Diana Bishop (Teresa Palmer) is an extremely bright and brilliant history lecturer at Oxford. The woman is also a witch, but does what she can to forget her origins. However, everything changes the day he comes into possession of the mysterious manuscript. To unravel the mystery connected with it, the historian collaborates with the enigmatic geneticist Matthew Clairmont (Matthew Goode). It quickly turns out that he also hides a dark family secret - he is a vampire. Their joint search puts the fragile peace that has existed for centuries between witches, vampires, demons and humans at risk.